Sarah Cooper and John Stubbs publish in ‘Chemical Physics Letters’
Sarah Cooper (Biochemistry and Neuroscience '15) and John Stubbs, Ph.D., associate professor of chemistry, recently published a paper in the journal Chemical Physics Letters.
The work, titled "The effect of unequal strand length on short DNA duplex hybridization in a model microarray system: A Monte Carlo simulation study,” investigated the impact of differing DNA strand lengths on DNA double helix stability when attached to a surface.
The results have implications for the design and interpretation of DNA sequence testing using microarray technology.