Denise Giuvelis, Nicholas McGlinchey and Ed Bilsky publish research article in ‘Journal of Medicinal Chemistry’

Three members of the Bilsky laboratory are co-authors on a recent article published in the Journal of Medicinal Chemistry. The paper, titled “14-Alkoxy- and 14-Acyloxypyridomophinans: Mixed Mu Agonist/Delta Antagonist Opioid Analgesics with Diminished Tolerance and Dependence Side Effects” investigated novel compounds for the treatment of acute and chronic pain.

The team that carried out the project included ֱ staff member Denise Giuvelis (’07), current COP student and CAS alum Nicholas McGlinchey and Edward Bilsky, Ph.D., associate provost for research and scholarship and professor of biomedical sciences in COM. The work was done in collaboration with long-time colleagues at Southern Research Institute and the National Institute on Drug Abuse.

Citation: Ananthan, S., Saini, S.K., Dersch, C.M., Xu, H., McGlinchey, N., Giuvelis, D., Bilsky, E.J. and Rothman, R.B. 14-Alkoxy- and 14-Acyloxypyridomophinans: Mixed Mu Agonist/Delta Antagonist Opioid Analgesics with Diminished Tolerance and Dependence Side Effects. Journal of Medicinal Chemistry. E-pub, September 2012.
 

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